Endothelial function in mild primary hyperparathyroidism

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Aortic valve calcification in mild primary hyperparathyroidism.

CONTEXT It is unclear whether cardiovascular disease is present in primary hyperparathyroidism (PHPT). OBJECTIVE Aortic valve structure and function were compared in PHPT patients and population-based controls. DESIGN This is a case-control study. SETTING The study was conducted in a university hospital metabolic bone disease unit. PARTICIPANTS We studied 51 patients with PHPT and 49 co...

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Cardiac function in mild primary hyperparathyroidism and the outcome after parathyroidectomy

OBJECTIVE Primary hyperparathyroidism (PHPT) is associated with cardiovascular morbidity. The extent of cardiovascular abnormalities in patients with mild-asymptomatic disease is unclear. Using sensitive echocardiographic methods, we compared cardiac structure and function in patients with mild PHPT and in healthy controls, and evaluated the changes after parathyroidectomy (PTX). METHODS In a...

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Lower quality of life in longstanding mild primary hyperparathyroidism.

OBJECTIVE To describe the non-classical manifestations and quality of life in patients with primary hyperparathyroidism (PHPT). SUBJECTS AND METHODS We evaluated non-classical manifestations and quality of life of 22 patients with PHPT using the SF-36 questionnaire according to the time since diagnosis. RESULTS In the scores of quality of life, a significant difference was found comparing t...

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Improvement in renal function in primary hyperparathyroidism following parathyroidectomy.

Glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) were measured pre- and post-parathyroidectomy in 9 patients with primary hyperparathyroidism. Radiological studies had shown no sign of renal calculi or nephrocalcinosis in these patients. Before operation, GFR ranged from 98.5 to 23.4 ml/min/1.7 m2 and ERPF ranged from 510 to 127 ml/min/1.7 m2. After operation, GFR rose to...

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Adenoma weight and biochemical parameters in primary hyperparathyroidism

 Abstract Background: Primary hyperparathyroidism is autonomous production of parathyroid hormone. After removal of adenoma, one of the surgeons concern is postoperative hypocalcaemia. There is no precise method to determine if patients have hypocalcaemia postoperatively. The purpose of this study was to determine the relation between parathyroid adenoma weights, postoperative serum calcium and...

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ژورنال

عنوان ژورنال: Clinical Endocrinology

سال: 2013

ISSN: 0300-0664

DOI: 10.1111/j.1365-2265.2012.04485.x